Growth differentiation factor-15, a novel systemic biomarker of oxidative stress, inflammation, and cellular aging: Potential role in cardiovascular diseases
Growth differentiation factor-15 (GDF-15) is a cytokine upregulated in multiple pathological conditions where oxidative stress, endothelial dysfunction, tissue aging, and chronic inflammation are the hallmarks. GDF-15 has many sources of production, including cardiac and vascular myocytes, endotheli...
Main Authors: | Angelo Michele di Candia, Diane Xavier de Avila, Gustavo Rodolfo Moreira, Humberto Villacorta, Alan S. Maisel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | American Heart Journal Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666602221000446 |
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