The Impact of Genetically Proxied AMPK Activation, the Target of Metformin, on Functional Outcome Following Ischemic Stroke

The Impact of Genetically Proxied AMPK Activation, the Target of Metformin, on Functional Outcome Following Ischemic Stroke

Background and Purpose We performed a two-sample Mendelian randomization (MR) analysis to evaluate the causal effect of genetically proxied AMP-activated protein kinase (AMPK) activation, which is the target of metformin, on functional outcome following ischemic stroke onset. Methods A total of 44 A...

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Bibliographic Details
Main Authors: Mengmeng Wang, Zhizhong Zhang, Marios K. Georgakis, Ville Karhunen, Dandan Liu
Format: Article
Language:English
Published: Korean Stroke Society 2023-05-01
Series:Journal of Stroke
Subjects:
mendelian randomization
stroke
metformin
drug-repurposing
Online Access:http://www.j-stroke.org/upload/pdf/jos-2022-03230.pdf

Internet

http://www.j-stroke.org/upload/pdf/jos-2022-03230.pdf

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