Upregulation of alpha7 Nicotinic Receptors by Acetylcholinesterase C-Terminal Peptides.

BACKGROUND: The alpha-7 nicotinic acetylcholine receptor (alpha7-nAChR) is well known as a potent calcium ionophore that, in the brain, has been implicated in excitotoxicity and hence in the underlying mechanisms of neurodegenerative disorders such as Alzheimer's disease. Previous research impl...

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Bibliographic Details
Main Authors: Cherie E Bond, Martina Zimmermann, Susan A Greenfield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2654408?pdf=render