Expression of DNA methyltransferases in adult dorsal root ganglia is cell-type specific and up regulated in a rodent model of neuropathic pain.

Neuropathic pain is associated with hyperexcitability and intrinsic firing of dorsal root ganglia (DRG) neurons. These phenotypical changes can be long lasting, potentially spanning the entire life of animal models, and depend on altered expression of numerous proteins, including many ion channels....

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Bibliographic Details
Main Authors: Sarah Lynn Pollema-Mays, Maria Virginia Centeno, A.Vania eApkarian, Marco eMartina
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00217/full