ASFV pA151R negatively regulates type I IFN production via degrading E3 ligase TRAF6

ASFV pA151R negatively regulates type I IFN production via degrading E3 ligase TRAF6

African swine fever (ASF) caused by African swine fever virus (ASFV) is a highly mortal and hemorrhagic infectious disease in pigs. Previous studies have indicated that ASFV modulates interferon (IFN) production. In this study, we demonstrated that ASFV pA151R negatively regulated type I IFN product...

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Bibliographic Details
Main Authors: You Li, Li Huang, Hui Li, Yingqi Zhu, Zilong Yu, Xiaojie Zheng, Changjiang Weng, Wen-hai Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
ASFV
type I IFN
pA151R
TBK1
TRAF6
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1339510/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1339510/full

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