Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle

Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle

In overloaded and regenerating muscle, the generation of new myonuclei depends on muscle satellite cells (MuSCs). Because MuSC behaviors in these two environments have not been considered separately, MuSC behaviors in overloaded muscle remain unexamined. Here, we show that most MuSCs in overloaded m...

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Bibliographic Details
Main Authors: Sumiaki Fukuda, Akihiro Kaneshige, Takayuki Kaji, Yu-taro Noguchi, Yusei Takemoto, Lidan Zhang, Kazutake Tsujikawa, Hiroki Kokubo, Akiyoshi Uezumi, Kazumitsu Maehara, Akihito Harada, Yasuyuki Ohkawa, So-ichiro Fukada
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
skeletal muscle
satellite cells
hypertrophy
Notch
Online Access:https://elifesciences.org/articles/48284

Internet

https://elifesciences.org/articles/48284

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