Proximity proteomics identifies PAK4 as a component of Afadin–Nectin junctions

PAK4 is a kinase involved in cell-cell junctions, though the identify of the  local protein network involving PAK4 is unclear. Here, the authors performed proximity proteomic analysis on mammalian PAK4 and find  that PAK4 is associated with Afadin-dependent junctions, and report putative PAK4 phosph...

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Bibliographic Details
Main Authors: Yohendran Baskaran, Felicia Pei-Ling Tay, Elsa Yuen Wai Ng, Claire Lee Foon Swa, Sheena Wee, Jayantha Gunaratne, Edward Manser
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25011-w