Predicting Drug Release From Degradable Hydrogels Using Fluorescence Correlation Spectroscopy and Mathematical Modeling

Predicting release from degradable hydrogels is challenging but highly valuable in a multitude of applications such as drug delivery and tissue engineering. In this study, we developed a simple mathematical and computational model that accounts for time-varying diffusivity and geometry to predict so...

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Bibliographic Details
Main Authors: Saahil Sheth, Emily Barnard, Ben Hyatt, Muruhan Rathinam, Silviya Petrova Zustiak
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00410/full