MAP3K8 is a potential therapeutic target in airway epithelial inflammation

MAP3K8 is a potential therapeutic target in airway epithelial inflammation

Abstract Background We have previously discovered clusters of sequentially negative and positive modulators of acute inflammation during cytokine stimulation in epithelial cells and identified potential targets for therapy within these clusters. MAP3K8 is a druggable kinase that we found to be a hub...

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Bibliographic Details
Main Authors: Chih-Yung Chiu, Saffron A. G. Willis-Owen, Kenny C.C. Wong, Stuart N. Farrow, William O.C. Cookson, Miriam F. Moffatt, Youming Zhang
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Journal of Inflammation
Subjects:
MAP3K8
Pathways
Epithelial cells
Inflammation
Online Access:https://doi.org/10.1186/s12950-024-00400-2

Internet

https://doi.org/10.1186/s12950-024-00400-2

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