A combined physicochemical approach towards human tenocyte phenotype maintenance

A combined physicochemical approach towards human tenocyte phenotype maintenance

During in vitro culture, bereft of their optimal tissue context, tenocytes lose their phenotype and function. Considering that tenocytes in their native tissue milieu are exposed simultaneously to manifold signals, combination approaches (e.g. growth factor supplementation and mechanical stimulation...

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Bibliographic Details
Main Authors: C.N.M. Ryan, E. Pugliese, N. Shologu, D. Gaspar, P. Rooney, Md N. Islam, A. O'Riordan, M.J. Biggs, M.D. Griffin, D.I. Zeugolis
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Materials Today Bio
Subjects:
Collagen type I coating
Surface topography
Substrate elasticity
Macromolecular crowding
Cell phenotype maintenance
In vitro microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006421000387

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http://www.sciencedirect.com/science/article/pii/S2590006421000387

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