Capicua regulates proliferation and survival of RB-deficient cells in Drosophila

Summary Mutations in rbf1, the Drosophila homologue of the RB tumour suppressor gene, generate defects in cell cycle control, cell death, and differentiation during development. Previous studies have established that EGFR/Ras activity is an important determinant of proliferation and survival in rbf1...

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Bibliographic Details
Main Authors: Kate Krivy, Mary-Rose Bradley-Gill, Nam-Sung Moon
Format: Article
Language:English
Published: The Company of Biologists 2012-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/2/183