Validation of Bone Marrow Derived Dendritic Cells as an Appropriate Model to Study Tumor-Mediated Suppression of DC Maturation through STAT3 Hyperactivation

PURPOSE: Tumors can escape immune eradication by harnessing dendritic cell (DC) maturation. However, DC types used as in vitro models to study tumor-mediated immunosuppression possess fundamental variability that could influence research outcomes. Therefore, we assessed the behavior of two distinct...

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Bibliographic Details
Main Authors: Aws Alshamsan, Samar Hamdy, Saswati Das Saswati Das, Afsaneh Lavasanifar, John Samuel, Ayman O.S. El-Kadi
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-02-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/6779