Identification of immune subsets with distinct lectin binding signatures using multi-parameter flow cytometry: correlations with disease activity in systemic lupus erythematosus

Identification of immune subsets with distinct lectin binding signatures using multi-parameter flow cytometry: correlations with disease activity in systemic lupus erythematosus

ObjectivesCell surface glycosylation can influence protein-protein interactions with particular relevance to changes in core fucosylation and terminal sialylation. Glycans are ligands for immune regulatory lectin families like galectins (Gals) or sialic acid immunoglobulin-like lectins (Siglecs). Th...

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Bibliographic Details
Main Authors: Enikő Szabó, Anna Faragó, Gergely Bodor, Nikolett Gémes, László G. Puskás, László Kovács, Gábor J. Szebeni
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
flow cytometry
glycobiology of SLE
lectin binding
immunophenotyping
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1380481/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1380481/full

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