A One-Step Sample Processing Method in Combination with HPLC-MS/MS for the Simultaneous Quantification of Atorvastatin, Ezetimibe and Three Metabolites including <i>o</i>-Hydroxyl Atorvastatin, <i>p</i>-Hydroxyl Atorvastatin, and Ezetimibe-Glucuronide in Human Plasma
A simple and sensitive liquid chromatography–tandem mass spectrometry (LC-MS/MS) method has been developed for the simultaneous determination of atorvastatin (ATOR), ezetimibe (EZM), and their three metabolites, including <i>o</i>-hydroxyl atorvastatin (<i>o</i>-OH ATOR), <...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-07-01
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| Series: | Separations |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2297-8739/10/7/409 |