A data-adaptive method for investigating effect heterogeneity with high-dimensional covariates in Mendelian randomization
Abstract Background Mendelian randomization is a popular method for causal inference with observational data that uses genetic variants as instrumental variables. Similarly to a randomized trial, a standard Mendelian randomization analysis estimates the population-averaged effect of an exposure on a...
| Auteurs principaux: | , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
BMC
2024-02-01
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| Collection: | BMC Medical Research Methodology |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1186/s12874-024-02153-1 |