Rapid and Affordable High Throughput Screening of SARS-CoV-2 Variants Using Denaturing High-Performance Liquid Chromatography Analysis

Rapid and Affordable High Throughput Screening of SARS-CoV-2 Variants Using Denaturing High-Performance Liquid Chromatography Analysis

Mutations in the receptor binding domain (RBD) of SARS-CoV-2 alter the infectivity, pathogenicity, and transmissibility of new variants of concern (VOCs). In addition, those mutations cause immune escape, undermining the population immunity induced by ongoing mass vaccination programs. There is an u...

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Bibliographic Details
Main Authors: Maria Elena Turba, Domenico Mion, Stavros Papadimitriou, Francesca Taddei, Giorgio Dirani, Vittorio Sambri, Fabio Gentilini
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Virology
Subjects:
SARS-CoV-2
denaturing high-performance liquid chromatography
variant of concern
surveillance
Receptor Binding Domain
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.889592/full

Internet

https://www.frontiersin.org/articles/10.3389/fviro.2022.889592/full

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