The coupling of mitoproteolysis and oxidative phosphorylation enables tracking of an active mitochondrial state through MitoTimer fluorescence

The coupling of mitoproteolysis and oxidative phosphorylation enables tracking of an active mitochondrial state through MitoTimer fluorescence

The regulation of mitochondria function and health is a central node in tissue maintenance, ageing as well as the pathogenesis of various diseases. However, the maintenance of an active mitochondrial functional state and its quality control mechanisms remain incompletely understood. By studying mice...

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Bibliographic Details
Main Authors: Yinyin Xie, Yannan Zhang, Aina Sun, Yamei Peng, Weikang Hou, Cong Xiang, Guoxin Zhang, Beibei Lai, Xiaoshuang Hou, Fangfang Zheng, Fan Wang, Geng Liu
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Redox Biology
Subjects:
Mitoproteolysis
MitoTimer
Oxidative metabolism
PGC-1α
Muscle fiber type
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722002191

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http://www.sciencedirect.com/science/article/pii/S2213231722002191

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