CAT-DTI: cross-attention and Transformer network with domain adaptation for drug-target interaction prediction

CAT-DTI: cross-attention and Transformer network with domain adaptation for drug-target interaction prediction

Abstract Accurate and efficient prediction of drug-target interaction (DTI) is critical to advance drug development and reduce the cost of drug discovery. Recently, the employment of deep learning methods has enhanced DTI prediction precision and efficacy, but it still encounters several challenges....

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Bibliographic Details
Main Authors: Xiaoting Zeng, Weilin Chen, Baiying Lei
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Bioinformatics
Subjects:
Drug-target interaction
Transformer
Cross-attention
Domain adaptation
Online Access:https://doi.org/10.1186/s12859-024-05753-2

Internet

https://doi.org/10.1186/s12859-024-05753-2

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