Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2

Abstract Background SARS-CoV-2, a positive-sense RNA virus in the family Coronaviridae, has caused a worldwide pandemic of coronavirus disease 2019 or COVID-19. Coronaviruses generate a tiered series of subgenomic RNAs (sgRNAs) through a process involving homology between transcriptional regulatory...

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Bibliographic Details
Main Authors: Jason Nomburg, Matthew Meyerson, James A. DeCaprio
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Genome Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13073-020-00802-w