Enhancement of Manufacturing Technology for Finished Dosage Form of Bivalent Chemical Tableted Cholera Vaccine

Objective of the study is to experimentally substantiate the possibility to improve manufacturing efficiency by means of mass reduction of a vaccine tablet from 300 to 100 mg. Materials and methods. Inaba O-antigen lyophilizate serves as the specific immunogenic component of the vaccine. Results and...

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Bibliographic Details
Main Authors: A. V. Komissarov, A. Yu. Ul’Yanov, O. A. Volokh, I. V. Shul’Gina, O. A. Lobovikova, O. D. Klokova, A. K. Nikiforov
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2016-03-01
Series:Проблемы особо опасных инфекций
Subjects:
Online Access:https://journal.microbe.ru/jour/article/view/294