Optimizing linear energy transfer distribution in intensity-modulated proton therapy using the alternating direction method of multipliers

Optimizing linear energy transfer distribution in intensity-modulated proton therapy using the alternating direction method of multipliers

PurposeThis study develop a novel linear energy transfer (LET) optimization method for intensity-modulated proton therapy (IMPT) with minimum monitor unit (MMU) constraint using the alternating direction method of multipliers (ADMM).Material and methodsThe novel LET optimization method (ADMM-LET) wa...

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Bibliographic Details
Main Authors: Qingkun Fan, Xiaoyuan Zhang, Riao Dao, Yujia Qian, Lewei Zhao, Xiaoqiang Li, Xuanfeng Ding, Gang Liu, Shuyang Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Oncology
Subjects:
intensity-modulated proton therapy (IMPT)
relative biological effectiveness (RBE)
linear energy transfer (LET)
treatment planning
alternating direction method of multipliers (ADMM)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1328147/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1328147/full

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