HOME: a histogram based machine learning approach for effective identification of differentially methylated regions

HOME: a histogram based machine learning approach for effective identification of differentially methylated regions

Abstract Background The development of whole genome bisulfite sequencing has made it possible to identify methylation differences at single base resolution throughout an entire genome. However, a persistent challenge in DNA methylome analysis is the accurate identification of differentially methylat...

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Váldodahkkit: Akanksha Srivastava, Yuliya V. Karpievitch, Steven R. Eichten, Justin O. Borevitz, Ryan Lister
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: BMC 2019-05-01
Ráidu:BMC Bioinformatics
Fáttát:
Whole genome bisulfite sequencing
DNA methylation
Epigenetics
DMR identification
SVM
Liŋkkat:http://link.springer.com/article/10.1186/s12859-019-2845-y

Interneahtta

http://link.springer.com/article/10.1186/s12859-019-2845-y

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