Identification of <i>NRAS</i> Downstream Genes with CRISPR Activation Screening

Identification of <i>NRAS</i> Downstream Genes with CRISPR Activation Screening

Mutations in <i>NRAS</i> constitutively activate cell proliferation signaling in malignant neoplasms, such as leukemia and melanoma, and the clarification of comprehensive downstream genes of <i>NRAS</i> might lead to the control of cell-proliferative signals of <i>NRAS...

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Bibliographic Details
Main Authors: Akiya Tatsumi, Haruka Hirakochi, Satomi Inoue, Yosuke Tanaka, Hidehiro Furuno, Masumi Ikeda, Sachiko Ishibashi, Towako Taguchi, Kouhei Yamamoto, Iichiroh Onishi, Zohar Sachs, David A. Largaespada, Masanobu Kitagawa, Morito Kurata
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biology
Subjects:
CRISPR screening
NRAS
Online Access:https://www.mdpi.com/2079-7737/11/11/1551

Internet

https://www.mdpi.com/2079-7737/11/11/1551

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