In vitro transdifferentiation of human peripheral blood mononuclear cells to photoreceptor-like cells

Direct reprogramming is a promising, simple and low-cost approach to generate target cells from somatic cells without using induced pluripotent stem cells. Recently, peripheral blood mononuclear cells (PBMCs) have attracted considerable attention as a somatic cell source for reprogramming. As a cell...

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Bibliographic Details
Main Authors: Yukari Komuta, Toshiyuki Ishii, Makoto Kaneda, Yasuji Ueda, Kiyoko Miyamoto, Masashi Toyoda, Akihiro Umezawa, Yuko Seko
Format: Article
Language:English
Published: The Company of Biologists 2016-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/5/6/709