Induction of broadly reactive influenza antibodies increases susceptibility to autoimmunity

Induction of broadly reactive influenza antibodies increases susceptibility to autoimmunity

Summary: Infection and vaccination repeatedly expose individuals to antigens that are conserved between influenza virus subtypes. Nevertheless, antibodies recognizing variable influenza epitopes greatly outnumber antibodies reactive against conserved epitopes. Elucidating factors contributing to the...

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Bibliographic Details
Main Authors: Jocelyn G. Labombarde, Meenu R. Pillai, Marie Wehenkel, Chun-Yang Lin, Rachael Keating, Scott A. Brown, Jeremy Chase Crawford, David C. Brice, Ashley H. Castellaw, Alexandra H. Mandarano, Clifford S. Guy, Juan R. Mejia, Carlessia D. Lewis, Ti-Cheng Chang, Christine M. Oshansky, Sook-San Wong, Richard J. Webby, Mei Yan, Quan–Zhen Li, Tony N. Marion, Paul G. Thomas, Maureen A. McGargill
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Cell Reports
Subjects:
influenza
autoimmunity
universal influenza vaccine
antibody
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722002157

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http://www.sciencedirect.com/science/article/pii/S2211124722002157

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