Case report and literature review: clinical manifestations and treatment of human RelA deficiency

Case report and literature review: clinical manifestations and treatment of human RelA deficiency

RelA deficiency resulting from mutations in the human RELA gene is a recently identified inborn errors of immunity (IEI). The RELA gene encodes the RelA (p65) protein, one of the five transcription factors of the NF-κB family, which plays a critical role in the regulation of transcriptional programs...

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Bibliographic Details
Main Authors: Chenghao Wang, Wenjie Wang, Xiaoying Hui, Jia Hou, Qinhua Zhou, Qifan Li, Qi Wu, Qi Ni, Bingbing Wu, Jinqiao Sun, Xiaochuan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
RelA deficiency
NF-κB
recurrent oral ulcers
Behçet’s disease
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1529654/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1529654/full

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