Endogenous Na+, K+-ATPase inhibitors and CSF [Na+] contribute to migraine formation.

Endogenous Na+, K+-ATPase inhibitors and CSF [Na+] contribute to migraine formation.

There is strong evidence that neuronal hyper-excitability underlies migraine, and may or may not be preceded by cortical spreading depression. However, the mechanisms for cortical spreading depression and/or migraine are not established. Previous studies reported that cerebrospinal fluid (CSF) [Na+]...

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Bibliographic Details
Main Authors: Noah B Gross, Nastaren Abad, David Lichtstein, Shiri Taron, Lorena Aparicio, Alfred N Fonteh, Xianghong Arakaki, Robert P Cowan, Samuel C Grant, Michael G Harrington
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218041

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https://doi.org/10.1371/journal.pone.0218041

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