Identification of Asiaticoside from <i>Centella erecta</i> (Apiaceae) as Potential Apyrase Inhibitor by UF-UHPLC-MS and Its In Vivo Antischistosomal Activity

Identification of Asiaticoside from <i>Centella erecta</i> (Apiaceae) as Potential Apyrase Inhibitor by UF-UHPLC-MS and Its In Vivo Antischistosomal Activity

Schistosomiasis, caused by parasites of the genus <i>Schistosoma</i>, is a neglected disease with high global prevalence, affecting more than 240 million people in several countries. Praziquantel (PZQ) is the only drug currently available for the treatment. <i>S. mansoni</i>...

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Bibliographic Details
Main Authors: Lara Soares Aleixo de Carvalho, Vinícius Carius de Souza, Vinícius C. Rodrigues, Aline Correa Ribeiro, Jorge Willian Leandro Nascimento, Priscila V. S. Z. Capriles, Priscila de F. Pinto, Josué de Moraes, Ademar Alves da Silva Filho
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceutics
Subjects:
<i>Schistosoma mansoni</i>
natural products
asiaticoside
Online Access:https://www.mdpi.com/1999-4923/14/5/1071

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https://www.mdpi.com/1999-4923/14/5/1071

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