ETS1 and HLHS: Implications for the Role of the Endocardium

We have identified the ETS1 gene as the cause of congenital heart defects, including an unprecedented high frequency of HLHS, in the chromosomal disorder Jacobsen syndrome. Studies in <i>Ciona intestinalis</i> demonstrated a critical role for ETS1 in heart cell fate determination and cel...

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Bibliographic Details
Main Author: Paul Grossfeld
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/9/7/219