Circulating Cell‐Free DNAs as a Biomarker and Therapeutic Target for Acetaminophen‐Induced Liver Injury

Circulating Cell‐Free DNAs as a Biomarker and Therapeutic Target for Acetaminophen‐Induced Liver Injury

Abstract Acetaminophen (APAP) overdose is a leading cause of drug‐induced liver injury and acute liver failure, while the detection, prognosis prediction, and therapy for APAP‐induced liver injury (AILI) remain improved. Here, it is determined that the temporal pattern of circulating cell‐free DNA (...

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Bibliographic Details
Main Authors: Madi Sun, Peiyu Chen, Kai Xiao, Xiang Zhu, Zhibin Zhao, Chenyang Guo, Xuan He, Tongfei Shi, Qingguo Zhong, Yong Jia, Yu Tao, Mingqiang Li, Kam W. Leong, Dan Shao
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Advanced Science
Subjects:
acetaminophen
acute liver injuries
biomarkers
cell‐free DNA
inflammation
oxidative damage
Online Access:https://doi.org/10.1002/advs.202206789

Internet

https://doi.org/10.1002/advs.202206789

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