Sesquiterpene nootkatone counteracted the melamine-induced neurotoxicity via repressing of oxidative stress, inflammatory, and apoptotic trajectories

Sesquiterpene nootkatone counteracted the melamine-induced neurotoxicity via repressing of oxidative stress, inflammatory, and apoptotic trajectories

Melamine (ML), a chemical substance of high nitrogen content, is used as a food adulterant. Former evidences implied that ML could induce a variety of toxic effects including neurotoxicity and cognitive impairment. Therefore, the aim of this study was to delineate the protective effect of the nootka...

Full description

Bibliographic Details
Main Authors: Ola A. Habotta, Ahmed Abdeen, Aya A. El-Hanafy, Neimet Yassin, Dina Elgameel, Samah F. Ibrahim, Doaa Abdelrahaman, Tabinda Hasan, Florin Imbrea, Heba I. Ghamry, Liana Fericean, Ali Behairy, Ahmed M. Atwa, Afaf Abdelkader, Mohamed R. Mahdi, Shaaban A. El-Mosallamy
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Sesquiterpene ketones
Melamine, neurotoxicity
Inflammation
Oxidative stress
HMGB-1/RAGE/TLR-4/NF-κB
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223009241

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223009241

Similar Items