Pre-diagnosis blood DNA methylation profiling of twin pairs discordant for breast cancer points to the importance of environmental risk factors

Pre-diagnosis blood DNA methylation profiling of twin pairs discordant for breast cancer points to the importance of environmental risk factors

Abstract Background Assessment of breast cancer (BC) risk generally relies on mammography, family history, reproductive history, and genotyping of major mutations. However, assessing the impact of environmental factors, such as lifestyle, health-related behavior, or external exposures, is still chal...

Full description

Bibliographic Details
Main Authors: Hannes Frederik Bode, Liang He, Jacob V. B. Hjelmborg, Jaakko Kaprio, Miina Ollikainen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Breast cancer
Survival analysis
Monozygotic twins
Dizygotic twins
Online Access:https://doi.org/10.1186/s13148-024-01767-y

Internet

https://doi.org/10.1186/s13148-024-01767-y

Similar Items