Synthetic anti-angiogenic genomic therapeutics for treatment of neovascular age-related macular degeneration

In light of the intriguing potential of anti-angiogenic approach in suppressing choroidal neovascularization, we attempted to elaborate synthetic gene delivery systems encapsulating anti-angiogenic plasmid DNA as alternatives of clinical antibody-based therapeutics. Herein, block copolymer of cyclic...

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Bibliographic Details
Main Authors: Jing Wang, Xiang Shi, Qiyu Bo, Hong Wang, Fang Wei, Jun Liu, Hao Wang, Liuwei Zhang, Yan Qi, Zhen Li, Qixian Chen, Xiaodong Sun
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087621000362