Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice

Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice

Abstract Microglia, the innate immune cells of the central nervous system, actively participate in brain development by supporting neuronal maturation and refining synaptic connections. These cells are emerging as highly metabolically flexible, able to oxidize different energetic substrates to meet...

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Bibliographic Details
Main Authors: Katia Monsorno, Kyllian Ginggen, Andranik Ivanov, An Buckinx, Arnaud L. Lalive, Anna Tchenio, Sam Benson, Marc Vendrell, Angelo D’Alessandro, Dieter Beule, Luc Pellerin, Manuel Mameli, Rosa Chiara Paolicelli
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41502-4

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https://doi.org/10.1038/s41467-023-41502-4

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