Moxibustion alleviates depression-like behavior in rats with Crohn’s disease by inhibiting the kynurenine pathway metabolism in the gut-brain axis

Moxibustion alleviates depression-like behavior in rats with Crohn’s disease by inhibiting the kynurenine pathway metabolism in the gut-brain axis

BackgroundMoxibustion is a potential therapy for inflammatory bowel disease-related depression, but its specific mechanism of action is unclear. This study aimed to investigate the molecular mechanism by which moxibustion alleviates depressive behavior in rats with Crohn’s disease (CD).MethodsThe CD...

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Bibliographic Details
Main Authors: Chunhui Bao, Jin Huang, Huangan Wu, Yueying Ma, Hongyu Zhou, Liming Chen, Dandan Yang, Huirong Liu, Yin Shi, Yuan Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Neuroscience
Subjects:
moxibustion
Crohn’s disease
depression
gut-brain axis
tryptophan-kynurenine metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.1019590/full

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https://www.frontiersin.org/articles/10.3389/fnins.2022.1019590/full

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