Actin Cytoskeleton and Integrin Components Are Interdependent for Slit Diaphragm Maintenance in <i>Drosophila</i> Nephrocytes

In nephrotic syndrome, the podocyte filtration structures are damaged in a process called foot process effacement. This is mediated by the actin cytoskeleton; however, which actins are involved and how they interact with other filtration components, like the basement membrane, remains poorly underst...

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Bibliographic Details
Main Authors: Megan Delaney, Yunpo Zhao, Joyce van de Leemput, Hangnoh Lee, Zhe Han
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/16/1350