Improving Transcriptome Fidelity Following Synovial Tissue Disaggregation

Improving Transcriptome Fidelity Following Synovial Tissue Disaggregation

ObjectiveTo improve the fidelity of the cellular transcriptome of disaggregated synovial tissue for applications such as single-cell RNA sequencing (scRNAseq) by modifying the disaggregation technique.MethodsOsteoarthritis (OA) and rheumatoid arthritis (RA) synovia were collected at arthroplasty. RN...

Full description

Bibliographic Details
Main Authors: David L. Boyle, Edward B. Prideaux, Joshua Hillman, Wei Wang, Gary S. Firestein
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Medicine
Subjects:
rheumatoid arthritis
synovia
functional genomics
transcriptome
disaggregation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.919748/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.919748/full

Similar Items