Development and Use of a Monoclonal Antibody Specific for the Candida albicans Cell-Surface Protein Hwp1

The Candida albicans cell-surface protein Hwp1 functions in adhesion to the host and in biofilm formation. A peptide from the Gln-Pro-rich adhesive domain of Hwp1 was used to raise monoclonal antibody (MAb) 2-E8. MAb 2-E8 specificity for Hwp1 was demonstrated using a hwp1/hwp1 C. albicans isolate an...

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Bibliographic Details
Main Authors: Soon-Hwan Oh, Hélène Martin-Yken, David A. Coleman, Etienne Dague, Lois L. Hoyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.907453/full