Derivation of a new model of lung adenocarcinoma using canine lung cancer organoids for translational research in pulmonary medicine

Derivation of a new model of lung adenocarcinoma using canine lung cancer organoids for translational research in pulmonary medicine

Canine primary lung cancer (cPLC) is a rare malignant tumor in dogs, and exhibits poor prognosis. Effective therapeutic drugs against cPLC have not been established yet. Also, cPLC resembles human lung cancer in histopathological characteristics and gene expression profiles and thus could be an impo...

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Bibliographic Details
Main Authors: Yomogi Shiota (Sato), Mohamed Elbadawy, Kazuhiko Suzuki, Ryouichi Tsunedomi, Hiroaki Nagano, Yusuke Ishihara, Haru Yamamoto, Daigo Azakami, Tsuyoshi Uchide, Ryuji Fukushima, Ryo Tanaka, Tomohiko Yoshida, Takuya Mori, Amira Abugomaa, Masahiro Kaneda, Hideyuki Yamawaki, Yuta Shinohara, Mohamed Aboubakr, Mohamed E. El-Asrag, Tatsuya Usui, Kazuaki Sasaki
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Organoids
Canine
Lung cancer
MEK inhibitor
RNA seq
C-MYC
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223008703

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http://www.sciencedirect.com/science/article/pii/S0753332223008703

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