(−)-Epicatechin Ameliorates Monosodium Urate-Induced Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and the NF-κB Signaling Pathway

(−)-Epicatechin Ameliorates Monosodium Urate-Induced Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and the NF-κB Signaling Pathway

Background: Gouty arthritis is a common and complex inflammatory disease that will reduce the life quality of human beings (−)-Epicatechin (EC) is famous for antioxidant and anti-inflammatory activities. Thus, the aim of this study was to investigate the therapeutic effect of EC on gouty arthritis a...

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Bibliographic Details
Main Authors: Chenxi Wu, Fenfen Li, Xiaoxi Zhang, Wenjing Xu, Yan Wang, Yanjing Yao, Ziwei Han, Daozong Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
anti-inflammatory
(−)-epicatechin
gouty arthritis
NF-κB signaling pathway
NLRP3 inflammasome
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.799552/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.799552/full

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