IL-37 Suppresses MyD88-mediated Inflammatory Responses in Human Aortic Valve Interstitial Cells

IL-37 Suppresses MyD88-mediated Inflammatory Responses in Human Aortic Valve Interstitial Cells

Abstract Calcific aortic valve disease (CAVD) is common among the elderly, and aortic valve interstitial cells (AVICs) exhibit unique inflammatory and osteogenic responses to proinflammatory stimulation, which plays an important role in valvular fibrosis and calcification. Thus, suppression of AVIC...

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Bibliographic Details
Main Authors: Qiong Zhan, Qingchun Zeng, Rui Song, Yufeng Zhai, Dingli Xu, David A. Fullerton, Charles A. Dinarello, Xianzhong Meng
Format: Article
Language:English
Published: BMC 2017-03-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2017.00022

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http://link.springer.com/article/10.2119/molmed.2017.00022

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