Prolonged glucocorticoid treatment in ARDS: impact on intensive care unit acquired weakness.

AbstractSystemic inflammation and duration of immobilization are strong independent risk factors for development of intensive care unit- acquired weakness (ICUAW). Activation of the pro-inflammatory transcription factor nuclear factor-κB (NF-κB) results in muscle wasting during disuse-induced skele...

Full description

Bibliographic Details
Main Authors: Gianfranco Umberto Meduri, Andreas Schwingshackl, Greet Hermans
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fped.2016.00069/full