Cannflavins A and B with Anti-Ferroptosis, Anti-Glycation, and Antioxidant Activities Protect Human Keratinocytes in a Cell Death Model with Erastin and Reactive Carbonyl Species

Cannflavins A and B with Anti-Ferroptosis, Anti-Glycation, and Antioxidant Activities Protect Human Keratinocytes in a Cell Death Model with Erastin and Reactive Carbonyl Species

Precursors of advanced glycation endproducts, namely, reactive carbonyl species (RCSs), are aging biomarkers that contribute to cell death. However, the impact of RCSs on ferroptosis—an iron-dependent form of cell death—in skin cells remains unknown. Herein, we constructed a cellular model (with hum...

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Bibliographic Details
Main Authors: Huifang Li, Ni Deng, Tess Puopolo, Xian Jiang, Navindra P. Seeram, Chang Liu, Hang Ma
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Nutrients
Subjects:
skin-aging
ferroptosis
reactive carbonyl species
proteomics
cell death
keratinocytes
Online Access:https://www.mdpi.com/2072-6643/15/21/4565

Internet

https://www.mdpi.com/2072-6643/15/21/4565

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