Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction

Kim, Hwang et al. use in vitro and in vivo models of autophagy disorder/metabolic dysfunction to show that in this context, the natural compound kaempferide is an autophagy enhancer and reveal that one of the underlying mechanisms governing this is mediated by the mitochondrial elongation factor TUF...

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Bibliographic Details
Main Authors: Dasol Kim, Hui-Yun Hwang, Eun Sun Ji, Jin Young Kim, Jong Shin Yoo, Ho Jeong Kwon
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01566-0