Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction
Kim, Hwang et al. use in vitro and in vivo models of autophagy disorder/metabolic dysfunction to show that in this context, the natural compound kaempferide is an autophagy enhancer and reveal that one of the underlying mechanisms governing this is mediated by the mitochondrial elongation factor TUF...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-01-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-020-01566-0 |