Pre-existing antibodies directed against a tetramerizing domain enhance the immune response against artificially stabilized soluble tetrameric influenza neuraminidase

Abstract The neuraminidase (NA) is an abundant antigen at the surface of influenza virions. Recent studies have highlighted the immune-protective potential of NA against influenza and defined anti-NA antibodies as an independent correlate of protection. Even though NA head domain changes at a slight...

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Váldodahkkit: João Paulo Portela Catani, Emma R. Job, Tine Ysenbaert, Anouk Smet, Satyajit Ray, Lauren LaRue, Svetlana Stegalkina, Mario Barro, Thorsten U. Vogel, Xavier Saelens
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Nature Portfolio 2022-01-01
Ráidu:npj Vaccines
Liŋkkat:https://doi.org/10.1038/s41541-022-00435-7