De novo lipogenesis in metabolic homeostasis: More friend than foe?
Background: An acute surplus of carbohydrates, and other substrates, can be converted and safely stored as lipids in adipocytes via de novo lipogenesis (DNL). However, in obesity, a condition characterized by chronic positive energy balance, DNL in non-adipose tissues may lead to ectopic lipid accum...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-05-01
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Series: | Molecular Metabolism |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877815000599 |