PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland

The origin and source of mammary gland progenitors and how they interact with the adipose‐rich stroma is unclear. Here, the authors identify PDGFRα+ adipocyte progenitors in the murine mammary stroma as a mesenchymal cell lineage recruited into the expanding epithelium during development, hormone ex...

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Bibliographic Details
Main Authors: Purna A. Joshi, Paul D. Waterhouse, Katayoon Kasaian, Hui Fang, Olga Gulyaeva, Hei Sook Sul, Paul C. Boutros, Rama Khokha
Format: Article
Language:English
Published: Nature Portfolio 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09748-z