Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation

Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 receptor 2 (IL-10R2). As the IL-22R1/IL-10R2 heterodimer is preferentially expressed on border tissue betw...

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Bibliographic Details
Main Authors: Masutaka Furue, Mihoko Furue
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2021-04-01
Series:Exploration of Immunology
Subjects:
Online Access:https://www.explorationpub.com/Journals/ei/Article/10035