Transcriptome Sequencing Identifies Novel Immune Response Genes Highly Related to the Severity of Human Adenovirus Type 55 Infection

Human adenovirus type 55 (HAdV-55) is considered a highly virulent pathogen causing severe and even deadly pneumonia in immunocompetent people. The mechanisms of HAdV-55-induced initiation and progression of severe pneumonia remain ambiguous. In the current study, we endeavored to identify novel imm...

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Bibliographic Details
Main Authors: Wen Xu, Zhe Xu, Lei Huang, En-Qiang Qin, Jie-li Zhang, Peng Zhao, Bo Tu, Lei Shi, Wen-Gang Li, Wei-Wei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00130/full