Dissecting Brainstem Locomotor Circuits: Converging Evidence for Cuneiform Nucleus Stimulation

There are a pressing and unmet need for effective therapies for freezing of gait (FOG) and other neurological gait disorders. Deep brain stimulation (DBS) of a midbrain target known as the pedunculopontine nucleus (PPN) was proposed as a potential treatment based on its postulated involvement in loc...

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Bibliographic Details
Main Authors: Stephano J. Chang, Iahn Cajigas, Ioan Opris, James D. Guest, Brian R. Noga
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnsys.2020.00064/full